Circulating H₂S levels are significantly lower in heart failure patients compared to age-matched controls in a prospective cohort study.

H₂S is Significantly Reduced in Heart Failure Patients


Lower plasma sulfide concentrations correlated with risk of heart failure, predicted greater NYHA class severity, higher mortality, greater rehospitalization rates, higher pro-BNP, and higher pulmonary artery systolic pressure (p<0.05).